A radiologic or nuclear event, such as an accident involving radioactive materials or a 'dirty bomb' explosion, could injure a large number of people. Emergency responders would need to rapidly screen and identify those who have been exposed to radiation. This will require a new kind of screening test to measure radiation effects on the human body.
The Biomedical Advanced Research and Development Authority (BARDA) has awarded Menssana Research Inc. a contract for $4.2 million. Studies in irradiated humans and animals have revealed a large number of breath biomarkers of radiation exposure.
The project’s long-term goal is to develop a rapid point-of-care test that could be used to rapidly screen large numbers of people for radiation exposure, and to determine the severity of the dose received in order to guide their medical care.
(PDF Document) A Dose-Dependent Hematological Evaluation of Whole-Body Gamma-Irradiation in the Göttingen Minipig.
Thrall KD, Murphy MK, Lovaglio J, Murphy MK, Cataneo RN, Chaturvedi A, Mundada M, Patel U, Phillips M
Health Physics Society Journal 105 (3): 245-252 (Sep. 2013)
(PDF Document) Detection of volatile biomarkers of therapeutic radiation in breath.
Phillips M, Byrnes R, Cataneo RN, Chaturvedi A, Kaplan PD, Libardoni M, Mehta V, Mundada M, Patel U, Ramakrishna N, Schiff PB, Zhang X
Journal of Breath Research (Jun. 24, 2013)